![\"\"](\"https:\/\/atlanticmedical.vn\/wp-content\/uploads\/2025\/08\/a-2.jpg\")
<\/figure>\n<\/figure>\n\n\n\nC\u00e1c lo\u1ea1i hormon estrogen<\/em><\/strong><\/h2>\n\n\n\nEstrogen l\u00e0m xu\u1ea5t hi\u1ec7n v\u00e0 b\u1ea3o t\u1ed3n \u201ct\u00ednh n\u1eef\u201d k\u1ec3 t\u1eeb tu\u1ed5i d\u1eady th\u00ec bao g\u1ed3m: ph\u00e1t tri\u1ec3n c\u01a1 quan sinh d\u1ee5c, l\u1edbp m\u1ee1 d\u01b0\u1edbi da, gi\u1ecdng n\u00f3i trong, d\u00e1ng m\u1ec1m m\u1ea1i\u2026<\/p>\n\n\n\n
2.1. Vai tr\u00f2 c\u1ee7a estrogen v\u1edbi kh\u1ea3 n\u0103ng sinh s\u1ea3n c\u1ee7a n\u1eef gi\u1edbi:<\/h2>\n\n\n\n\n![\"\"](\"https:\/\/atlanticmedical.vn\/wp-content\/uploads\/2025\/08\/c.png\")
<\/figure>\n<\/figure>\n\n\n\nVai tr\u00f2 estrogen v\u1edbi kh\u1ea3 n\u0103ng sinh s\u1ea3n<\/em><\/strong><\/p>\n\n\n\n\u2013 Tuy\u1ebfn v\u00fa: H\u00ecnh th\u00e0nh c\u00e1c m\u00f4 tuy\u1ebfn v\u00fa, ph\u00e1t tri\u1ec3n c\u00e1c \u1ed1ng d\u1eabn s\u1eefa, gi\u00fap ng\u01b0ng ti\u1ebft s\u1eefa sau khi tr\u1ebb cai s\u1eefa.<\/p>\n\n\n\n
\u2013 Bu\u1ed3ng tr\u1ee9ng: K\u00edch th\u00edch s\u1ef1 ph\u00e1t tri\u1ec3n, tr\u01b0\u1edfng th\u00e0nh c\u1ee7a c\u00e1c nang tr\u1ee9ng, nh\u1edd \u0111\u00f3 x\u1ea3y ra hi\u1ec7n t\u01b0\u1ee3ng r\u1ee5ng tr\u1ee9ng.<\/p>\n\n\n\n
\u2013 \u1ed0ng d\u1eabn tr\u1ee9ng: L\u00e0m d\u00e0y th\u00e0nh c\u01a1 tr\u01a1n trong \u1ed1ng d\u1eabn tr\u1ee9ng, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho vi\u1ec7c th\u1ee5 tinh v\u00e0 l\u00e0m t\u1ed5.<\/p>\n\n\n\n
\u2013 C\u1ed5 t\u1eed cung: \u0110i\u1ec1u ch\u1ec9nh l\u01b0u l\u01b0\u1ee3ng, \u0111\u1ed9 d\u00e0y v\u00e0 l\u00e0m cho ch\u1ea5t nh\u1ea7y c\u1ed5 t\u1eed cung tr\u1edf n\u00ean lo\u00e3ng v\u00e0 ki\u1ec1m. Nh\u1edd \u0111\u00f3, tinh tr\u00f9ng di chuy\u1ec3n \u0111\u1ebfn tr\u1ee9ng d\u1ec5 d\u00e0ng h\u01a1n, qu\u00e1 tr\u00ecnh th\u1ee5 tinh thu\u1eadn l\u1ee3i h\u01a1n.<\/p>\n\n\n\n
\u2013 T\u1eed cung: T\u0103ng c\u01b0\u1eddng v\u00e0 duy tr\u00ec m\u00e0ng nh\u1ea7y b\u00ean trong l\u00f2ng t\u1eed cung, k\u00edch th\u00edch c\u00e1c c\u01a1 t\u1eed cung ph\u00e1t tri\u1ec3n v\u00e0 co b\u00f3p. \u0110i\u1ec1u n\u00e0y c\u1ea7n thi\u1ebft trong qu\u00e1 tr\u00ecnh sinh n\u1edf v\u00e0 c\u0169ng h\u1ed7 tr\u1ee3 lo\u1ea1i b\u1ecf c\u00e1c t\u1ebf b\u00e0o ch\u1ebft trong l\u00f2ng t\u1eed cung trong chu k\u1ef3 kinh nguy\u1ec7t.<\/p>\n\n\n\n
\u2013 \u00c2m \u0111\u1ea1o: Duy tr\u00ec \u0111\u1ed9 d\u00e0y c\u1ee7a th\u00e0nh \u00e2m \u0111\u1ea1o v\u00e0 th\u00fac \u0111\u1ea9y b\u00f4i tr\u01a1n \u00e2m \u0111\u1ea1o t\u1eeb \u0111\u00f3 t\u0103ng c\u01b0\u1eddng k\u00edch th\u00edch, t\u0103ng kho\u00e1i c\u1ea3m t\u00ecnh d\u1ee5c, gi\u1eef cho \u00e2m \u0111\u1ea1o m\u1ec1m m\u1ea1i v\u00e0 gi\u1ea3m ma s\u00e1t trong ho\u1ea1t \u0111\u1ed9ng t\u00ecnh d\u1ee5c \u1edf n\u1eef gi\u1edbi.<\/p>\n\n\n\n
2.2. Vai tr\u00f2 c\u1ee7a estrogen v\u1edbi c\u00e1c c\u01a1 quan kh\u00e1c trong c\u01a1 th\u1ec3:<\/h2>\n\n\n\n\n![\"\"](\"https:\/\/atlanticmedical.vn\/wp-content\/uploads\/2025\/08\/v.jpg\")
<\/figure>\n<\/figure>\n\n\n\nVai tr\u00f2 c\u1ee7a estrogen v\u1edbi c\u00e1c c\u01a1 quan kh\u00e1c<\/em><\/strong><\/p>\n\n\n\n\u2013 Da: K\u00edch th\u00edch s\u1ea3n xu\u1ea5t collagen v\u00e0 t\u0103ng \u0111\u1ed9 \u1ea9m c\u1ee7a da, gi\u00fap da c\u0103ng b\u00f3ng v\u00e0 kh\u1ecfe m\u1ea1nh, l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a v\u00e0 c\u00e1c n\u1ebfp nh\u0103n.<\/p>\n\n\n\n
\u2013 T\u00f3c: Estrogen l\u00e0 m\u1ed9t trong 4 lo\u1ea1i hormon c\u00f3 \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn qu\u00e1 tr\u00ecnh m\u1ecdc v\u00e0 r\u1ee5ng t\u00f3c.<\/p>\n\n\n\n
\u2013 C\u01a1 x\u01b0\u01a1ng: Tham gia v\u00e0o qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n chi\u1ec1u cao \u1edf \u0111\u1ed9 tu\u1ed5i d\u1eady th\u00ec, l\u00e0m n\u1edf r\u1ed9ng khung x\u01b0\u01a1ng ch\u1eadu, \u0111\u1ed3ng th\u1eddi t\u0103ng l\u1eafng \u0111\u1ecdng mu\u1ed1i canxi-phosphat \u1edf x\u01b0\u01a1ng, gi\u00fap duy tr\u00ec c\u1ea5u tr\u00fac x\u01b0\u01a1ng. Do \u0111\u00f3, khi n\u1ed3ng \u0111\u1ed9 estrogen suy gi\u1ea3m v\u1ec1 m\u1ee9c th\u1ea5p, ng\u01b0\u1eddi ph\u1ee5 n\u1eef s\u1ebd t\u0103ng nguy c\u01a1 lo\u00e3ng x\u01b0\u01a1ng v\u00e0 bi\u1ebfn d\u1ea1ng c\u1ed9t s\u1ed1ng.<\/p>\n\n\n\n
\u2013 N\u00e3o: Estrogen th\u00fac \u0111\u1ea9y gi\u00e3n m\u1ea1ch, t\u1ea3n nhi\u1ec7t v\u00e0 h\u1ea1 nhi\u1ec7t \u0111\u1ed9 c\u01a1 th\u1ec3. S\u1ef1 thi\u1ebfu h\u1ee5t estrogen c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c c\u01a1n b\u1ed1c h\u1ecfa, v\u00e3 m\u1ed3 h\u00f4i. Ngo\u00e0i ra, estrogen g\u00f3p ph\u1ea7n duy tr\u00ec ch\u1ee9c n\u0103ng n\u00e3o b\u1ed9, l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh \u0111\u00e3ng tr\u00ed khi tu\u1ed5i t\u00e1c t\u0103ng l\u00ean. M\u1ed9t s\u1ed1 t\u00e0i li\u1ec7u cho th\u1ea5y estrogen gi\u00fap gi\u1ea3m nguy c\u01a1 ph\u00e1t tri\u1ec3n b\u1ec7nh Alzheimer \u1edf ph\u1ee5 n\u1eef.<\/p>\n\n\n\n
\u2013 Tim m\u1ea1ch: \u0111i\u1ec1u ch\u1ec9nh qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t cholesterol c\u1ee7a gan, t\u0103ng \u201cm\u1ee1 t\u1ed1t \u2013 HDL\u201d, gi\u1ea3m \u201cm\u1ee1 x\u1ea5u \u2013 LDL\u201d v\u00e0 t\u0103ng s\u1ee9c b\u1ec1n th\u00e0nh m\u1ea1ch.<\/p>\n\n\n\n
\u2013 H\u1ec7 ti\u1ebft ni\u1ec7u: t\u0103ng c\u01b0\u1eddng v\u00e0 duy tr\u00ec l\u1edbp bi\u1ec3u m\u00f4 c\u1ee7a ni\u1ec7u \u0111\u1ea1o (\u1ed1ng d\u1eabn n\u01b0\u1edbc ti\u1ec3u t\u1eeb b\u00e0ng quang ra ngo\u00e0i) gi\u00fap b\u1ea3o v\u1ec7 b\u00e0ng quang, ti\u1ebft ni\u1ec7u kh\u1ecfi s\u1ef1 x\u00e2m nh\u1eadp c\u1ee7a vi khu\u1ea9n.<\/p>\n\n\n\n
3. Bi\u1ec3u hi\u1ec7n r\u1ed1i lo\u1ea1n estrogen v\u1edbi ph\u1ee5 n\u1eef?<\/h2>\n\n\n\n3.1. T\u0103ng ti\u1ebft estrogen.<\/h2>\n\n\n\n
T\u00ecnh tr\u1ea1ng t\u0103ng n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef th\u01b0\u1eddng g\u1eb7p \u1edf nh\u1eefng ph\u1ee5 n\u1eef m\u1eafc h\u1ed9i ch\u1ee9ng bu\u1ed3ng tr\u1ee9ng \u0111a nang (Polycystic Ovary Syndrome \u2013 PCOS).<\/p>\n\n\n\n
Tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng bu\u1ed3ng tr\u1ee9ng \u0111a nang c\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u trong giai \u0111o\u1ea1n d\u1eady th\u00ec, g\u1ed3m thi\u1ebfu kinh, v\u00f4 kinh, r\u1eadm l\u00f4ng nh\u01b0 nam gi\u1edbi. B\u00ean c\u1ea1nh \u0111\u00f3, nh\u1eefng ng\u01b0\u1eddi m\u1eafc PCOS ph\u1ea3i \u0111\u1ed1i m\u1eb7t nguy c\u01a1 m\u1eafc nh\u1eefng v\u1ea5n \u0111\u1ec1 s\u1ee9c kho\u1ebb nghi\u00eam tr\u1ecdng nh\u01b0: v\u00f4 sinh, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2, b\u1ec7nh tim m\u1ea1ch, b\u00e9o ph\u00ec, m\u1ee1 m\u00e1u, r\u1ed1i lo\u1ea1n kinh nguy\u1ec7t\u2026<\/p>\n\n\n\n
3.2. Gi\u1ea3m estrogen<\/h2>\n\n\n\n
M\u1ed7i n\u0103m c\u00f3 h\u00e0ng tri\u1ec7u ph\u1ee5 n\u1eef tr\u00ean kh\u1eafp th\u1ebf gi\u1edbi \u0111ang ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi t\u00ecnh tr\u1ea1ng suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1. T\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 do nh\u1eefng nguy\u00ean nh\u00e2n kh\u00e1c nhau:<\/p>\n\n\n\n
\u2013 Di truy\u1ec1n: m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1 di truy\u1ec1n (thi\u1ebfu h\u1ee5t aromatase, h\u1ed9i ch\u1ee9ng Fragile X, h\u1ed9i ch\u1ee9ng Turner\u2026) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef<\/p>\n\n\n\n
\u2013 C\u01b0\u1eddng gi\u00e1p: c\u00f3 th\u1ec3 l\u00e0m gi\u00e1n \u0111o\u1ea1n c\u01a1 ch\u1ebf k\u00edch th\u00edch r\u1ee5ng tr\u1ee9ng h\u00e0ng th\u00e1ng, g\u00e2y t\u00ecnh tr\u1ea1ng thi\u1ebfu kinh ho\u1eb7c kh\u00f4ng c\u00f3 k\u1ef3 kinh nguy\u1ec7t<\/p>\n\n\n\n
\u2013 Suy tuy\u1ebfn y\u00ean: g\u00e2y thi\u1ebfu h\u1ee5t hormon truy\u1ec1n t\u00edn hi\u1ec7u bu\u1ed3ng tr\u1ee9ng t\u1ea1o estrogen, d\u1eabn \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 estrogen trong c\u01a1 th\u1ec3 th\u1ea5p<\/p>\n\n\n\n
\u2013 C\u1eaft b\u1ecf bu\u1ed3ng tr\u1ee9ng: ph\u1ea7n l\u1edbn estrogen trong c\u01a1 th\u1ec3 ph\u1ee5 n\u1eef do bu\u1ed3ng tr\u1ee9ng s\u1ea3n xu\u1ea5t. Do \u0111\u00f3, ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf bu\u1ed3ng tr\u1ee9ng g\u00e2y ra t\u00ecnh tr\u1ea1ng thi\u1ebfu h\u1ee5t estrogen.<\/p>\n\n\n\n
\u2013 X\u1ea1 tr\u1ecb: c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 nh\u01b0 h\u00f3a tr\u1ecb, x\u1ea1 tr\u1ecb \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng bu\u1ed3ng tr\u1ee9ng, l\u01b0\u1ee3ng estrogen \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t kh\u00f4ng \u0111\u1ee7 \u0111\u00e1p \u1ee9ng.<\/p>\n\n\n\n
\u2013 T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c: m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c (rifampicin, barbiturat, warfarin, carbamazepin, griseofulvin\u2026) l\u00e0m t\u0103ng c\u01b0\u1eddng \u0111\u00e0o th\u1ea3i estrogen t\u1ea1i gan.<\/p>\n\n\n\n
\u2013 L\u1ed1i s\u1ed1ng: nhi\u1ec1u nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra s\u1ef1 suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 c\u00f3 th\u1ec3 g\u00e2y ra b\u1edfi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, tinh th\u1ea7n c\u0103ng th\u1eb3ng.<\/p>\n\n\n\n
\u2013 Tu\u1ed5i: khi ph\u1ee5 n\u1eef b\u01b0\u1edbc v\u00e0o giai \u0111o\u1ea1n ti\u1ec1n m\u00e3n kinh, n\u1ed3ng \u0111\u1ed9 estrogen b\u1ecb suy gi\u1ea3m do bu\u1ed3ng tr\u1ee9ng suy tho\u00e1i v\u00e0 vi\u1ec7c s\u1ea3n xu\u1ea5t estrogen gi\u1ea3m d\u1ea7n. \u0110\u00e2y l\u00e0 nguy\u00ean nh\u00e2n ph\u1ed5 bi\u1ebfn nh\u1ea5t g\u00e2y ra suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef.<\/p>\n\n\n\n
S\u1ef1 suy gi\u1ea3m estrogen d\u1eabn \u0111\u1ebfn nhi\u1ec1u bi\u1ec3u hi\u1ec7n kh\u00e1c nhau v\u00e0 c\u00f3 th\u1ec3 kh\u00e1c nhau v\u1edbi t\u1eebng ng\u01b0\u1eddi nh\u01b0: b\u1ed1c ho\u1ea3, m\u1ec7t m\u1ecfi, kh\u00f3 ng\u1ee7, v\u00e3 m\u1ed3 h\u00f4i, thay \u0111\u1ed5i t\u00e2m tr\u1ea1ng, s\u1ea1m n\u00e1m da, suy gi\u1ea3m sinh l\u00fd, \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t\u2026nh\u01b0ng nh\u00ecn chung c\u00e1c bi\u1ec3u hi\u1ec7n n\u00e0y \u0111\u1ec1u t\u00e1c \u0111\u1ed9ng l\u00e0m gi\u1ea3m ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng ng\u01b0\u1eddi ph\u1ee5 n\u1eef. \u0110\u1ec3 gi\u1ea3m nh\u1eb9 t\u00ecnh tr\u1ea1ng suy gi\u1ea3m estrogen, ch\u1ecb em c\u00f3 th\u1ec3 tham kh\u1ea3o th\u00eam c\u00e1c C\u00e1ch t\u0103ng estrogen hi\u1ec7u qu\u1ea3<\/a><\/p>\n\n\n\n
<\/figure>\n<\/figure>\n\n\n\nVai tr\u00f2 estrogen v\u1edbi kh\u1ea3 n\u0103ng sinh s\u1ea3n<\/em><\/strong><\/p>\n\n\n\n \u2013 Tuy\u1ebfn v\u00fa: H\u00ecnh th\u00e0nh c\u00e1c m\u00f4 tuy\u1ebfn v\u00fa, ph\u00e1t tri\u1ec3n c\u00e1c \u1ed1ng d\u1eabn s\u1eefa, gi\u00fap ng\u01b0ng ti\u1ebft s\u1eefa sau khi tr\u1ebb cai s\u1eefa.<\/p>\n\n\n\n \u2013 Bu\u1ed3ng tr\u1ee9ng: K\u00edch th\u00edch s\u1ef1 ph\u00e1t tri\u1ec3n, tr\u01b0\u1edfng th\u00e0nh c\u1ee7a c\u00e1c nang tr\u1ee9ng, nh\u1edd \u0111\u00f3 x\u1ea3y ra hi\u1ec7n t\u01b0\u1ee3ng r\u1ee5ng tr\u1ee9ng.<\/p>\n\n\n\n \u2013 \u1ed0ng d\u1eabn tr\u1ee9ng: L\u00e0m d\u00e0y th\u00e0nh c\u01a1 tr\u01a1n trong \u1ed1ng d\u1eabn tr\u1ee9ng, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n thu\u1eadn l\u1ee3i cho vi\u1ec7c th\u1ee5 tinh v\u00e0 l\u00e0m t\u1ed5.<\/p>\n\n\n\n \u2013 C\u1ed5 t\u1eed cung: \u0110i\u1ec1u ch\u1ec9nh l\u01b0u l\u01b0\u1ee3ng, \u0111\u1ed9 d\u00e0y v\u00e0 l\u00e0m cho ch\u1ea5t nh\u1ea7y c\u1ed5 t\u1eed cung tr\u1edf n\u00ean lo\u00e3ng v\u00e0 ki\u1ec1m. Nh\u1edd \u0111\u00f3, tinh tr\u00f9ng di chuy\u1ec3n \u0111\u1ebfn tr\u1ee9ng d\u1ec5 d\u00e0ng h\u01a1n, qu\u00e1 tr\u00ecnh th\u1ee5 tinh thu\u1eadn l\u1ee3i h\u01a1n.<\/p>\n\n\n\n \u2013 T\u1eed cung: T\u0103ng c\u01b0\u1eddng v\u00e0 duy tr\u00ec m\u00e0ng nh\u1ea7y b\u00ean trong l\u00f2ng t\u1eed cung, k\u00edch th\u00edch c\u00e1c c\u01a1 t\u1eed cung ph\u00e1t tri\u1ec3n v\u00e0 co b\u00f3p. \u0110i\u1ec1u n\u00e0y c\u1ea7n thi\u1ebft trong qu\u00e1 tr\u00ecnh sinh n\u1edf v\u00e0 c\u0169ng h\u1ed7 tr\u1ee3 lo\u1ea1i b\u1ecf c\u00e1c t\u1ebf b\u00e0o ch\u1ebft trong l\u00f2ng t\u1eed cung trong chu k\u1ef3 kinh nguy\u1ec7t.<\/p>\n\n\n\n \u2013 \u00c2m \u0111\u1ea1o: Duy tr\u00ec \u0111\u1ed9 d\u00e0y c\u1ee7a th\u00e0nh \u00e2m \u0111\u1ea1o v\u00e0 th\u00fac \u0111\u1ea9y b\u00f4i tr\u01a1n \u00e2m \u0111\u1ea1o t\u1eeb \u0111\u00f3 t\u0103ng c\u01b0\u1eddng k\u00edch th\u00edch, t\u0103ng kho\u00e1i c\u1ea3m t\u00ecnh d\u1ee5c, gi\u1eef cho \u00e2m \u0111\u1ea1o m\u1ec1m m\u1ea1i v\u00e0 gi\u1ea3m ma s\u00e1t trong ho\u1ea1t \u0111\u1ed9ng t\u00ecnh d\u1ee5c \u1edf n\u1eef gi\u1edbi.<\/p>\n\n\n\n Vai tr\u00f2 c\u1ee7a estrogen v\u1edbi c\u00e1c c\u01a1 quan kh\u00e1c<\/em><\/strong><\/p>\n\n\n\n \u2013 Da: K\u00edch th\u00edch s\u1ea3n xu\u1ea5t collagen v\u00e0 t\u0103ng \u0111\u1ed9 \u1ea9m c\u1ee7a da, gi\u00fap da c\u0103ng b\u00f3ng v\u00e0 kh\u1ecfe m\u1ea1nh, l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e3o h\u00f3a v\u00e0 c\u00e1c n\u1ebfp nh\u0103n.<\/p>\n\n\n\n \u2013 T\u00f3c: Estrogen l\u00e0 m\u1ed9t trong 4 lo\u1ea1i hormon c\u00f3 \u1ea3nh h\u01b0\u1edfng tr\u1ef1c ti\u1ebfp \u0111\u1ebfn qu\u00e1 tr\u00ecnh m\u1ecdc v\u00e0 r\u1ee5ng t\u00f3c.<\/p>\n\n\n\n \u2013 C\u01a1 x\u01b0\u01a1ng: Tham gia v\u00e0o qu\u00e1 tr\u00ecnh ph\u00e1t tri\u1ec3n chi\u1ec1u cao \u1edf \u0111\u1ed9 tu\u1ed5i d\u1eady th\u00ec, l\u00e0m n\u1edf r\u1ed9ng khung x\u01b0\u01a1ng ch\u1eadu, \u0111\u1ed3ng th\u1eddi t\u0103ng l\u1eafng \u0111\u1ecdng mu\u1ed1i canxi-phosphat \u1edf x\u01b0\u01a1ng, gi\u00fap duy tr\u00ec c\u1ea5u tr\u00fac x\u01b0\u01a1ng. Do \u0111\u00f3, khi n\u1ed3ng \u0111\u1ed9 estrogen suy gi\u1ea3m v\u1ec1 m\u1ee9c th\u1ea5p, ng\u01b0\u1eddi ph\u1ee5 n\u1eef s\u1ebd t\u0103ng nguy c\u01a1 lo\u00e3ng x\u01b0\u01a1ng v\u00e0 bi\u1ebfn d\u1ea1ng c\u1ed9t s\u1ed1ng.<\/p>\n\n\n\n \u2013 N\u00e3o: Estrogen th\u00fac \u0111\u1ea9y gi\u00e3n m\u1ea1ch, t\u1ea3n nhi\u1ec7t v\u00e0 h\u1ea1 nhi\u1ec7t \u0111\u1ed9 c\u01a1 th\u1ec3. S\u1ef1 thi\u1ebfu h\u1ee5t estrogen c\u00f3 th\u1ec3 g\u00e2y ra c\u00e1c c\u01a1n b\u1ed1c h\u1ecfa, v\u00e3 m\u1ed3 h\u00f4i. Ngo\u00e0i ra, estrogen g\u00f3p ph\u1ea7n duy tr\u00ec ch\u1ee9c n\u0103ng n\u00e3o b\u1ed9, l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh \u0111\u00e3ng tr\u00ed khi tu\u1ed5i t\u00e1c t\u0103ng l\u00ean. M\u1ed9t s\u1ed1 t\u00e0i li\u1ec7u cho th\u1ea5y estrogen gi\u00fap gi\u1ea3m nguy c\u01a1 ph\u00e1t tri\u1ec3n b\u1ec7nh Alzheimer \u1edf ph\u1ee5 n\u1eef.<\/p>\n\n\n\n \u2013 Tim m\u1ea1ch: \u0111i\u1ec1u ch\u1ec9nh qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t cholesterol c\u1ee7a gan, t\u0103ng \u201cm\u1ee1 t\u1ed1t \u2013 HDL\u201d, gi\u1ea3m \u201cm\u1ee1 x\u1ea5u \u2013 LDL\u201d v\u00e0 t\u0103ng s\u1ee9c b\u1ec1n th\u00e0nh m\u1ea1ch.<\/p>\n\n\n\n \u2013 H\u1ec7 ti\u1ebft ni\u1ec7u: t\u0103ng c\u01b0\u1eddng v\u00e0 duy tr\u00ec l\u1edbp bi\u1ec3u m\u00f4 c\u1ee7a ni\u1ec7u \u0111\u1ea1o (\u1ed1ng d\u1eabn n\u01b0\u1edbc ti\u1ec3u t\u1eeb b\u00e0ng quang ra ngo\u00e0i) gi\u00fap b\u1ea3o v\u1ec7 b\u00e0ng quang, ti\u1ebft ni\u1ec7u kh\u1ecfi s\u1ef1 x\u00e2m nh\u1eadp c\u1ee7a vi khu\u1ea9n.<\/p>\n\n\n\n T\u00ecnh tr\u1ea1ng t\u0103ng n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef th\u01b0\u1eddng g\u1eb7p \u1edf nh\u1eefng ph\u1ee5 n\u1eef m\u1eafc h\u1ed9i ch\u1ee9ng bu\u1ed3ng tr\u1ee9ng \u0111a nang (Polycystic Ovary Syndrome \u2013 PCOS).<\/p>\n\n\n\n Tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng bu\u1ed3ng tr\u1ee9ng \u0111a nang c\u00f3 th\u1ec3 b\u1eaft \u0111\u1ea7u trong giai \u0111o\u1ea1n d\u1eady th\u00ec, g\u1ed3m thi\u1ebfu kinh, v\u00f4 kinh, r\u1eadm l\u00f4ng nh\u01b0 nam gi\u1edbi. B\u00ean c\u1ea1nh \u0111\u00f3, nh\u1eefng ng\u01b0\u1eddi m\u1eafc PCOS ph\u1ea3i \u0111\u1ed1i m\u1eb7t nguy c\u01a1 m\u1eafc nh\u1eefng v\u1ea5n \u0111\u1ec1 s\u1ee9c kho\u1ebb nghi\u00eam tr\u1ecdng nh\u01b0: v\u00f4 sinh, \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng tu\u00fdp 2, b\u1ec7nh tim m\u1ea1ch, b\u00e9o ph\u00ec, m\u1ee1 m\u00e1u, r\u1ed1i lo\u1ea1n kinh nguy\u1ec7t\u2026<\/p>\n\n\n\n M\u1ed7i n\u0103m c\u00f3 h\u00e0ng tri\u1ec7u ph\u1ee5 n\u1eef tr\u00ean kh\u1eafp th\u1ebf gi\u1edbi \u0111ang ph\u1ea3i \u0111\u1ed1i m\u1eb7t v\u1edbi t\u00ecnh tr\u1ea1ng suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1. T\u00ecnh tr\u1ea1ng n\u00e0y c\u00f3 th\u1ec3 do nh\u1eefng nguy\u00ean nh\u00e2n kh\u00e1c nhau:<\/p>\n\n\n\n \u2013 Di truy\u1ec1n: m\u1ed9t s\u1ed1 y\u1ebfu t\u1ed1 di truy\u1ec1n (thi\u1ebfu h\u1ee5t aromatase, h\u1ed9i ch\u1ee9ng Fragile X, h\u1ed9i ch\u1ee9ng Turner\u2026) c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef<\/p>\n\n\n\n \u2013 C\u01b0\u1eddng gi\u00e1p: c\u00f3 th\u1ec3 l\u00e0m gi\u00e1n \u0111o\u1ea1n c\u01a1 ch\u1ebf k\u00edch th\u00edch r\u1ee5ng tr\u1ee9ng h\u00e0ng th\u00e1ng, g\u00e2y t\u00ecnh tr\u1ea1ng thi\u1ebfu kinh ho\u1eb7c kh\u00f4ng c\u00f3 k\u1ef3 kinh nguy\u1ec7t<\/p>\n\n\n\n \u2013 Suy tuy\u1ebfn y\u00ean: g\u00e2y thi\u1ebfu h\u1ee5t hormon truy\u1ec1n t\u00edn hi\u1ec7u bu\u1ed3ng tr\u1ee9ng t\u1ea1o estrogen, d\u1eabn \u0111\u1ebfn n\u1ed3ng \u0111\u1ed9 estrogen trong c\u01a1 th\u1ec3 th\u1ea5p<\/p>\n\n\n\n \u2013 C\u1eaft b\u1ecf bu\u1ed3ng tr\u1ee9ng: ph\u1ea7n l\u1edbn estrogen trong c\u01a1 th\u1ec3 ph\u1ee5 n\u1eef do bu\u1ed3ng tr\u1ee9ng s\u1ea3n xu\u1ea5t. Do \u0111\u00f3, ph\u1eabu thu\u1eadt c\u1eaft b\u1ecf bu\u1ed3ng tr\u1ee9ng g\u00e2y ra t\u00ecnh tr\u1ea1ng thi\u1ebfu h\u1ee5t estrogen.<\/p>\n\n\n\n \u2013 X\u1ea1 tr\u1ecb: c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 nh\u01b0 h\u00f3a tr\u1ecb, x\u1ea1 tr\u1ecb \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng bu\u1ed3ng tr\u1ee9ng, l\u01b0\u1ee3ng estrogen \u0111\u01b0\u1ee3c s\u1ea3n xu\u1ea5t kh\u00f4ng \u0111\u1ee7 \u0111\u00e1p \u1ee9ng.<\/p>\n\n\n\n \u2013 T\u00e1c d\u1ee5ng ph\u1ee5 c\u1ee7a thu\u1ed1c: m\u1ed9t s\u1ed1 lo\u1ea1i thu\u1ed1c (rifampicin, barbiturat, warfarin, carbamazepin, griseofulvin\u2026) l\u00e0m t\u0103ng c\u01b0\u1eddng \u0111\u00e0o th\u1ea3i estrogen t\u1ea1i gan.<\/p>\n\n\n\n \u2013 L\u1ed1i s\u1ed1ng: nhi\u1ec1u nghi\u00ean c\u1ee9u \u0111\u00e3 ch\u1ec9 ra s\u1ef1 suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 c\u00f3 th\u1ec3 g\u00e2y ra b\u1edfi ch\u1ebf \u0111\u1ed9 \u0103n u\u1ed1ng, tinh th\u1ea7n c\u0103ng th\u1eb3ng.<\/p>\n\n\n\n \u2013 Tu\u1ed5i: khi ph\u1ee5 n\u1eef b\u01b0\u1edbc v\u00e0o giai \u0111o\u1ea1n ti\u1ec1n m\u00e3n kinh, n\u1ed3ng \u0111\u1ed9 estrogen b\u1ecb suy gi\u1ea3m do bu\u1ed3ng tr\u1ee9ng suy tho\u00e1i v\u00e0 vi\u1ec7c s\u1ea3n xu\u1ea5t estrogen gi\u1ea3m d\u1ea7n. \u0110\u00e2y l\u00e0 nguy\u00ean nh\u00e2n ph\u1ed5 bi\u1ebfn nh\u1ea5t g\u00e2y ra suy gi\u1ea3m n\u1ed9i ti\u1ebft t\u1ed1 n\u1eef.<\/p>\n\n\n\n S\u1ef1 suy gi\u1ea3m estrogen d\u1eabn \u0111\u1ebfn nhi\u1ec1u bi\u1ec3u hi\u1ec7n kh\u00e1c nhau v\u00e0 c\u00f3 th\u1ec3 kh\u00e1c nhau v\u1edbi t\u1eebng ng\u01b0\u1eddi nh\u01b0: b\u1ed1c ho\u1ea3, m\u1ec7t m\u1ecfi, kh\u00f3 ng\u1ee7, v\u00e3 m\u1ed3 h\u00f4i, thay \u0111\u1ed5i t\u00e2m tr\u1ea1ng, s\u1ea1m n\u00e1m da, suy gi\u1ea3m sinh l\u00fd, \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t\u2026nh\u01b0ng nh\u00ecn chung c\u00e1c bi\u1ec3u hi\u1ec7n n\u00e0y \u0111\u1ec1u t\u00e1c \u0111\u1ed9ng l\u00e0m gi\u1ea3m ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng ng\u01b0\u1eddi ph\u1ee5 n\u1eef. \u0110\u1ec3 gi\u1ea3m nh\u1eb9 t\u00ecnh tr\u1ea1ng suy gi\u1ea3m estrogen, ch\u1ecb em c\u00f3 th\u1ec3 tham kh\u1ea3o th\u00eam c\u00e1c C\u00e1ch t\u0103ng estrogen hi\u1ec7u qu\u1ea3<\/a><\/p>\n\n\n\n2.2. Vai tr\u00f2 c\u1ee7a estrogen v\u1edbi c\u00e1c c\u01a1 quan kh\u00e1c trong c\u01a1 th\u1ec3:<\/h2>\n\n\n\n
<\/figure>\n<\/figure>\n\n\n\n3. Bi\u1ec3u hi\u1ec7n r\u1ed1i lo\u1ea1n estrogen v\u1edbi ph\u1ee5 n\u1eef?<\/h2>\n\n\n\n
3.1. T\u0103ng ti\u1ebft estrogen.<\/h2>\n\n\n\n
3.2. Gi\u1ea3m estrogen<\/h2>\n\n\n\n