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Estrogen is one of the important female hormones, mainly produced by the ovaries from puberty, in addition to being present in the placenta and in the adrenal gland. There are three types of estrogen, with concentrations depending on the stage in a woman's life:
Estrogen appears and preserves "femininity" since puberty, including: development of genital organs, subcutaneous fat layer, clear voice, soft figure...
– Mammary gland: Forms mammary tissue, develops milk ducts, helps stop milk secretion after the baby is weaned.
– Ovaries: Stimulates the development and maturation of ovarian follicles, thereby causing ovulation to occur.
– Fallopian tube: Thickens the smooth muscle wall in the fallopian tube, creating favorable conditions for fertilization and implantation.
– Cervical: Regulates flow, thickness and makes cervical mucus thin and alkaline. Thanks to that, the sperm moves to the egg more easily, making the fertilization process more convenient.
– Uterus: Strengthens and maintains the mucous membrane inside the uterus, stimulating uterine muscles to develop and contract. This is necessary during childbirth and also aids in the removal of dead cells in the uterine lining during the menstrual cycle.
– Vagina: Maintains the thickness of the vaginal wall and promotes vaginal lubrication, thereby enhancing stimulation, increasing sexual pleasure, keeping the vagina soft and reducing friction during sexual activity in women. .
– Skin: Stimulates collagen production and increases skin moisture, making skin shiny and healthy, slowing down the aging process and wrinkles.
– Hair: Estrogen is one of four hormones that directly affect hair growth and loss.
– Skeletal muscle: Participates in the process of height development during puberty, widens the pelvis, and increases calcium-phosphate salt deposition in bones, helping to maintain bone structure. Therefore, when estrogen levels decrease to low levels, women will increase the risk of osteoporosis and spinal deformity.
– Brain: Estrogen promotes vasodilation, heat dissipation and lowers body temperature. Estrogen deficiency can cause hot flashes and sweating. In addition, estrogen contributes to maintaining brain function, slowing down the process of forgetfulness as age increases. Some literature suggests that estrogen helps reduce the risk of developing Alzheimer's disease in women.
– Cardiovascular: regulates the liver's cholesterol production process, increases "good fat - HDL", reduces "bad fat - LDL" and increases vessel wall strength.
– Urinary system: strengthens and maintains the epithelial layer of the urethra (the tube that carries urine from the bladder to the outside) to help protect the bladder and urinary tract from bacterial invasion.
Increased female hormones are common in women with Polycystic Ovary Syndrome (PCOS).
Symptoms of polycystic ovary syndrome can begin during puberty, including lack of menstruation, amenorrhea, and hirsutism like men. Besides, people with PCOS face the risk of serious health problems such as infertility, type 2 diabetes, cardiovascular disease, obesity, blood fat, menstrual disorders...
Every year, millions of women around the world are facing hormonal decline. This condition can be due to different causes:
– Genetics: some genetic factors (aromatase deficiency, Fragile X syndrome, Turner syndrome...) can reduce female hormones
– Hyperthyroidism: can disrupt the monthly ovulation stimulation mechanism, causing amenorrhea or no menstrual period.
– Hypopituitarism: causes a deficiency in the hormone that signals the ovaries to create estrogen, leading to low estrogen levels in the body
– Ovarian removal: most of the estrogen in a woman's body is produced by the ovaries. Therefore, surgical removal of the ovaries causes estrogen deficiency.
– Radiation therapy: cancer treatment methods such as chemotherapy and radiotherapy affect ovarian function, the amount of estrogen produced is not enough.
– Side effects of drugs: some drugs (rifampicin, barbiturates, warfarin, carbamazepine, griseofulvin...) enhance the elimination of estrogen in the liver.
– Lifestyle: many studies have shown that hormonal decline can be caused by diet and mental stress.
– Age: when women enter premenopause, estrogen levels decrease due to ovarian deterioration and estrogen production gradually decreases. This is the most common cause of female hormone deficiency.
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